Friday, October 7, 2016

Desoxyn


Pronunciation: meth-am-FET-ah-meen
Generic Name: Methamphetamine
Brand Name: Desoxyn

Desoxyn has a high risk for abuse. Long-term use of Desoxyn may lead to dependence. Use Desoxyn only as prescribed and do not share it with others.





Desoxyn is used for:

Treating attention deficit disorders with hyperactivity in children. It is also used on short-term basis (ie, a few weeks) in combination with other treatments to treat obesity. Desoxyn may also be used for other conditions as determined by your doctor.


Desoxyn is a central nervous system stimulant. The exact way it works is unknown. It controls the release of certain chemicals in the brain that affect mood, behavior, and appetite.


Do NOT use Desoxyn if:


  • you are allergic to any ingredient in Desoxyn

  • you have anorexia, symptomatic heart disease, moderate to severe high blood pressure, narrowing of your arteries, glaucoma, uncontrolled high blood pressure, an overactive thyroid, a history of drug or substance abuse, or you are agitated

  • you are taking guanethidine or you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using Desoxyn:


Some medical conditions may interact with Desoxyn. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of mental or mood problems, heart problems, the blood disease porphyria, seizures, or high blood pressure

Some MEDICINES MAY INTERACT with Desoxyn. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Furazolidone, MAO inhibitors (eg, phenelzine), or urinary alkalinizers (eg, sodium bicarbonate) because side effects, including increased blood pressure, dizziness, and decreased heart rate, may occur

  • Phenothiazines (eg, chlorpromazine) because they may decrease Desoxyn's effectiveness

  • Insulin, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), or tricyclic antidepressants (eg, amitriptyline) because the risk of their side effects may be increased by Desoxyn

  • Guanethidine because its effectiveness may be decreased by Desoxyn

This may not be a complete list of all interactions that may occur. Ask your health care provider if Desoxyn may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Desoxyn:


Use Desoxyn as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Desoxyn comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Desoxyn refilled.

  • Take Desoxyn by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

  • Take Desoxyn 10 to 14 hours before bedtime unless your doctor tells you differently.

  • If you miss a dose of Desoxyn, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Desoxyn.



Important safety information:


  • Desoxyn may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Desoxyn with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Do NOT take more than the recommended dose or take for longer than prescribed without checking with your doctor.

  • Desoxyn may cause sleeplessness. Do not take Desoxyn late in the day.

  • Avoid large amounts of food or drink that have caffeine (eg, coffee, tea, cocoa, cola, chocolate). Caffeine can increase the side effects of Desoxyn.

  • Check the labels on all your medicines (eg, cough-and-cold products, diet aids) because they may contain ingredients that could increase your heart rate or blood pressure. Ask your pharmacist about the safe use of these products.

  • Diabetes patients - Desoxyn may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

  • Tell your doctor or dentist that you take Desoxyn before you receive any medical or dental care, emergency care, or surgery.

  • Desoxyn may interfere with certain lab tests, including corticosteroid levels. Be sure your doctor and lab personnel know you are taking Desoxyn.

  • Desoxyn may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they take Desoxyn.

  • Desoxyn should not be used in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: It is not known if Desoxyn can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Desoxyn while you are pregnant. Desoxyn is found in breast milk. Do not breast-feed while taking Desoxyn.

When used for long periods of time or at high doses, Desoxyn may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Desoxyn stops working well. Do not take more than prescribed.


Some people who use Desoxyn for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction.


If you stop taking Desoxyn suddenly, you may have WITHDRAWAL symptoms. These may include severe tiredness, weakness, and mental depression.



Possible side effects of Desoxyn:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; diarrhea; dizziness; dry mouth; exaggerated sense of well-being; headache; loss of appetite; mild nervousness; nausea; upset stomach.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation or restlessness; blurred vision; change in sexual ability or desire; changes in speech; chest pain; difficulty moving; fainting; fast or irregular heartbeat; fever; mental/mood changes; pounding in chest; seizures; severe headaches; shortness of breath; stomach pain; tremor; trouble sleeping; uncontrolled muscle movements (eg, tics); unusual weakness or tiredness; vomiting.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Desoxyn side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; fast breathing; severe mental/mood changes; severe or persistent headache; severe restlessness.


Proper storage of Desoxyn:

Store Desoxyn at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep in a tightly closed container. Do not store in the bathroom. Keep Desoxyn out of the reach of children and away from pets.


General information:


  • If you have any questions about Desoxyn, please talk with your doctor, pharmacist, or other health care provider.

  • Desoxyn is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Desoxyn. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Desoxyn resources


  • Desoxyn Side Effects (in more detail)
  • Desoxyn Dosage
  • Desoxyn Use in Pregnancy & Breastfeeding
  • Drug Images
  • Desoxyn Drug Interactions
  • Desoxyn Support Group
  • 8 Reviews for Desoxyn - Add your own review/rating


  • Desoxyn Prescribing Information (FDA)

  • Desoxyn Advanced Consumer (Micromedex) - Includes Dosage Information

  • Desoxyn Concise Consumer Information (Cerner Multum)

  • Desoxyn Monograph (AHFS DI)

  • Methamphetamine Prescribing Information (FDA)



Compare Desoxyn with other medications


  • ADHD
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Desonate


Generic Name: desonide (Topical application route)

DES-oh-nide

Commonly used brand name(s)

In the U.S.


  • Desonate

  • Desowen

  • LoKara

  • Tridesilon

  • Verdeso

In Canada


  • Pms-Desonide

Available Dosage Forms:


  • Gel/Jelly

  • Ointment

  • Cream

  • Foam

  • Lotion

Therapeutic Class: Corticosteroid, Strong


Pharmacologic Class: Adrenal Glucocorticoid


Uses For Desonate


Desonide topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions (e.g., atopic dermatitis). This medicine is a corticosteroid (cortisone-like medicine or steroid).


This medicine is available only with your doctor's prescription.


Before Using Desonate


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of desonide topical foam or gel in children 3 months of age and older. However, because of this medicine's toxicity, it should be used with caution. Children may absorb large amounts through the skin, which can cause serious side effects. If your child is using this medicine, follow your doctor's instructions very carefully. For the foam and gel forms, safety and efficacy have not been established in infants younger than 3 months of age. The safety and efficacy of desonide topical cream, lotion, and ointment have not been established in children and use is not recommended.


Geriatric


No information is available on the relationship of age to the effects of desonide topical cream, ointment, or lotion in geriatric patients.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of desonide topical foam or gel in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution in patients receiving desonide topical foam or gel.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.


Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Cushing's syndrome (adrenal gland disorder) or

  • Diabetes or

  • Hyperglycemia (high blood sugar) or

  • Intracranial hypertension (increased pressure in the head)—Use with caution. May make these conditions worse.

  • Infection of the skin at or near the place of application or

  • Large sores, broken skin, or severe skin injury at the place of application—The chance of side effects may be increased.

Proper Use of desonide

This section provides information on the proper use of a number of products that contain desonide. It may not be specific to Desonate. Please read with care.


It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.


This medicine is for use on the skin only. Do not get it in your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.


This medicine should only be used for skin conditions that your doctor is treating. Check with your doctor before using it for other conditions, especially if you think that a skin infection may be present. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns.


Do not use the topical gel on the groin or underarms unless directed to do so by your doctor, and do not use this form for more than 4 weeks.


To use cream, gel, lotion, or ointment:


  • Wash your hands with soap and water before and after using this medicine.

  • Apply a thin layer of this medicine to the affected area of the skin. Rub it in gently.

  • With the lotion, protect the skin from water, clothing, or anything that causes rubbing until the medicine has dried. Also, shake the lotion well before using it.

  • Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor.

  • If the medicine is applied to the diaper area of an infant, do not use tight-fitting diapers or plastic pants unless directed to do so by your doctor.

To use the foam:


  • Wash your hands with soap and water before and after using this medicine.

  • Shake the foam well before using it.

  • Do not put the foam directly on your face. Turn the can upside down and place a small amount of medicine in your hands. Massage it gently into the affected areas of the face until the medicine has dried. For areas other than the face, you may put it directly on the affected area.

  • Do not wash or rinse the treated area right after applying the medicine.

  • Do not use this medicine near heat, an open flame, or while smoking.

Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For atopic dermatitis:
    • For topical dosage forms (foam or gel):
      • Adults and teenagers—Apply to the affected area of the skin two times per day.

      • Children 3 months of age and older—Apply to the affected area of the skin two times per day.

      • Children younger than 3 months of age—Use and dose must be determined by your doctor.



  • For redness, itching, and swelling of the skin:
    • For topical dosage forms (cream, ointment, or lotion):
      • Adults—Apply to the affected area of the skin two or three times per day.

      • Children—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.


Storage


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Store the foam can at room temperature, away from heat and direct light. Do not keep this medicine inside a car where it could be exposed to extreme heat. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.


Precautions While Using Desonate


It is very important that your doctor check the progress of you or your child at regular visits for any unwanted effects that may be caused by this medicine.


If your or your child's symptoms do not improve within a few days, or if they become worse, check with your doctor.


Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and patients who use large amounts for a long time. Talk to your doctor right away if you or your child have more than one of these symptoms while you are using this medicine: blurred vision; dizziness or fainting; a fast, irregular, or pounding heartbeat; increased thirst or urination; irritability; or unusual tiredness or weakness.


Stop using this medicine and check with your doctor right away if you or your child have a skin rash, burning, stinging, swelling, or irritation on the skin.


Make sure your doctor knows that you are using desonide foam. You may need to stop using this medicine several days before having surgery.


Do not use cosmetics or other skin care products on the treated areas.


Desonate Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


Less common
  • Blistering, burning, crusting, dryness, or flaking of the skin

  • burning, itching, redness, skin rash, swelling, or soreness at the application site

  • flushing or redness of the skin

  • irritation

  • itching, scaling, severe redness, soreness, or swelling of the skin

  • peeling of the skin

  • raised, dark red, wart-like spots on the skin, especially when used on the face

  • stinging and burning

  • unusually warm skin

Incidence not known
  • Redness and scaling around the mouth

  • thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (e.g., between the fingers)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Body aches or pain

  • chills

  • cough

  • difficulty with breathing

  • ear congestion

  • fever

  • headache

  • loss of voice

  • nasal congestion

  • runny nose

  • sneezing

  • sore throat

  • unusual tiredness or weakness

Less common
  • Cold flu-like symptoms

  • congestion

  • cough

  • hoarseness

  • irritability

  • noisy breathing

  • shortness of breath

  • tender, swollen glands in the neck

  • tightness in the chest

  • trouble with swallowing

  • voice changes

  • wheezing

Incidence not known
  • Acne or pimples

  • burning and itching of the skin with pinhead-sized red blisters

  • burning, itching, and pain in hairy areas, or pus at the root of the hair

  • lightening of normal skin color

  • lightening of treated areas of dark skin

  • reddish purple lines on the arms, face, legs, trunk, or groin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Desonate side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Desonate resources


  • Desonate Side Effects (in more detail)
  • Desonate Use in Pregnancy & Breastfeeding
  • Desonate Drug Interactions
  • Desonate Support Group
  • 0 Reviews for Desonate - Add your own review/rating


  • Desonate Gel MedFacts Consumer Leaflet (Wolters Kluwer)

  • Desonate Consumer Overview

  • Desonate Prescribing Information (FDA)

  • DesOwen Cream MedFacts Consumer Leaflet (Wolters Kluwer)

  • DesOwen Cream Kit Cream MedFacts Consumer Leaflet (Wolters Kluwer)

  • Desowen Prescribing Information (FDA)

  • LoKara Prescribing Information (FDA)

  • LoKara Lotion MedFacts Consumer Leaflet (Wolters Kluwer)

  • Verdeso Prescribing Information (FDA)

  • Verdeso Consumer Overview

  • Verdeso Foam MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Desonate with other medications


  • Atopic Dermatitis
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Dex PC


Generic Name: chlorpheniramine, dextromethorphan, and phenylephrine (klor feh NEER a meen, dex troe meh THOR fan, and feh nill EH frin)

Brand Names: Alka-Seltzer Plus Cold and Cough, C-Phen DM, C-Phen DM Drops, Cardec DM, Cardec DM Drops, Ceron-DM, Ceron-DM Drops, Cerose DM, Corfen-DM, CP Dec DM, CP Dec-DM Drops, De-Chlor DM, De-Chlor DR, Dec-Chlorphen DM, Dex PC, DM-PE-Chlor, Donatussin DM Drops, Ed A-Hist DM, HistadecDM, Maxiphen ADT, Mintuss DR, Nasohist-DM, Neo DM Drops, Nohist-DMX, Norel DM, P Chlor DM, PD-Cof, PD-Cof Drops, Poly-Tussin DM, Quartuss DM, Reme Tussin DM, Rondec-DM, Rondec-DM Drops, Rondex-DM, Rondex-DM Drops, Sildec-PE DM, Sildec-PE DM Drops, Tri-Vent DPC, Trital DM, Tussplex DM, Zotex-12D


What is Dex PC (chlorpheniramine, dextromethorphan, and phenylephrine)?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.


Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.


Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).


Chlorpheniramine, dextromethorphan, and phenylephrine is used to treat sneezing, cough, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.


Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.


Chlorpheniramine, dextromethorphan, and phenylephrine may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about Dex PC (chlorpheniramine, dextromethorphan, and phenylephrine)?


Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body. Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant. Chlorpheniramine, dextromethorphan, and phenylephrine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of this medication.

What should I discuss with my healthcare provider before taking Dex PC (chlorpheniramine, dextromethorphan, and phenylephrine)?


Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

Before taking this medication, tell your doctor if you are allergic to chlorpheniramine, dextromethorphan, or phenylephrine, or if you have:


  • kidney disease;

  • liver disease;


  • diabetes;




  • glaucoma;




  • heart disease or high blood pressure;




  • diabetes;




  • a thyroid disorder;




  • a stomach ulcer or a stomach obstruction,




  • emphysema or chronic bronchitis; or




  • an enlarged prostate or urination problems.



If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.


FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Chlorpheniramine, dextromethorphan, and phenylephrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cough-and-cold medications may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.


How should I take Dex PC (chlorpheniramine, dextromethorphan, and phenylephrine)?


Use this medication exactly as directed on the label or as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.


Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Take this medicine with a full glass of water. If you use the effervescent tablet, drop the tablet in 8 ounces of water and allow it to dissolve completely. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.


Take this medicine with food or milk if it upsets your stomach.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.


Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.


Store the medication at room temperature away from moisture and heat.

What happens if I miss a dose?


Since cough or cold medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).


What should I avoid while taking Dex PC (chlorpheniramine, dextromethorphan, and phenylephrine)?


This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of this medication. Before taking this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by this medication.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.


Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. Antihistamines, decongestants, and cough suppressants are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant.

Dex PC (chlorpheniramine, dextromethorphan, and phenylephrine) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat;




  • confusion, hallucinations, unusual thoughts or behavior;




  • severe dizziness, anxiety, restless feeling, or nervousness;




  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);




  • confusion, hallucinations;




  • slow, shallow breathing;




  • urinating less than usual or not at all;




  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or




  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).



Less serious side effects may include:



  • blurred vision;




  • dry mouth;




  • nausea, stomach pain, constipation;




  • mild loss of appetite, stomach upset;




  • warmth, tingling, or redness under your skin;




  • feeling excited or restless;




  • sleep problems (insomnia);




  • restless or excitability (especially in children);




  • skin rash or itching;




  • dizziness, drowsiness;




  • problems with memory or concentration; or




  • ringing in your ears.



This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Dex PC (chlorpheniramine, dextromethorphan, and phenylephrine)?


Before taking this medication, tell your doctor if you are using any of the following drugs:



  • an antidepressant;




  • a diuretic (water pill);




  • medication to treat irritable bowel syndrome;




  • celecoxib (Celebrex);




  • cinacalcet (Sensipar);




  • imatinib (Gleevec);




  • quinidine (Quinaglute, Quinidex);




  • ranolazine (Ranexa)




  • ritonavir (Norvir);




  • sibutramine (Meridia);




  • terbinafine (Lamisil);




  • medicines to treat high blood pressure;




  • aspirin or salicylates (such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others);




  • bladder or urinary medications such as darifenacin (Enablex), oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol); or




  • a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others.



This list is not complete and there may be other drugs that can interact with chlorpheniramine, dextromethorphan, and phenylephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.



More Dex PC resources


  • Dex PC Side Effects (in more detail)
  • Dex PC Use in Pregnancy & Breastfeeding
  • Dex PC Drug Interactions
  • Dex PC Support Group
  • 0 Reviews for Dex PC - Add your own review/rating


  • Bronkids Drops MedFacts Consumer Leaflet (Wolters Kluwer)

  • Cardec DM Elixir MedFacts Consumer Leaflet (Wolters Kluwer)

  • Ceron-DM Liquid MedFacts Consumer Leaflet (Wolters Kluwer)

  • Maxiphen ADT MedFacts Consumer Leaflet (Wolters Kluwer)

  • Quartuss DM Prescribing Information (FDA)

  • Trital DM Prescribing Information (FDA)



Compare Dex PC with other medications


  • Cough and Nasal Congestion


Where can I get more information?


  • Your pharmacist can provide more information about chlorpheniramine, dextromethorphan, and phenylephrine.

See also: Dex PC side effects (in more detail)


Desyrel



Generic Name: trazodone (Oral route)

TRAZ-oh-done

Oral route(Tablet;Tablet, Extended Release)

Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults in short-term studies with major depressive disorder (MDD) and other psychiatric disorders. Short term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24, and there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. This risk must be balanced with the clinical need. Monitor patients closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Not approved for use in pediatric patients .



Commonly used brand name(s)

In the U.S.


  • Desyrel

  • Desyrel Dividose

  • Oleptro

Available Dosage Forms:


  • Tablet

  • Tablet, Extended Release

Therapeutic Class: Antidepressant


Chemical Class: Triazolopyridine


Uses For Desyrel


Trazodone belongs to the group of medicines known as antidepressants or "mood elevators". It is used to relieve mental depression, and depression that sometimes occurs with anxiety.


This medicine is available only with your doctor's prescription.


Before Using Desyrel


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of trazodone in the pediatric population. Safety and efficacy have not been established.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of trazodone extended-release tablets in the elderly. However, elderly patients are more likely to have hyponatremia (low sodium in the blood), which may require caution in patients receiving trazodone.


No information is available on the relationship of age to the effects of trazodone regular tablets in the elderly.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.


  • Cisapride

  • Dronedarone

  • Linezolid

  • Metoclopramide

  • Pimozide

  • Posaconazole

  • Saquinavir

  • Sparfloxacin

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Alfuzosin

  • Amiodarone

  • Amitriptyline

  • Amoxapine

  • Apomorphine

  • Arsenic Trioxide

  • Asenapine

  • Astemizole

  • Azithromycin

  • Chloroquine

  • Ciprofloxacin

  • Citalopram

  • Clomipramine

  • Clozapine

  • Crizotinib

  • Dasatinib

  • Desipramine

  • Disopyramide

  • Dofetilide

  • Dolasetron

  • Droperidol

  • Duloxetine

  • Erythromycin

  • Flecainide

  • Fluconazole

  • Fluoxetine

  • Gatifloxacin

  • Gemifloxacin

  • Ginkgo

  • Granisetron

  • Halofantrine

  • Haloperidol

  • Ibutilide

  • Iloperidone

  • Imipramine

  • Lapatinib

  • Levofloxacin

  • Lopinavir

  • Lumefantrine

  • Mefloquine

  • Methadone

  • Methylene Blue

  • Moxifloxacin

  • Nilotinib

  • Norfloxacin

  • Nortriptyline

  • Octreotide

  • Ondansetron

  • Paliperidone

  • Paroxetine

  • Pazopanib

  • Perflutren Lipid Microsphere

  • Procainamide

  • Propafenone

  • Protriptyline

  • Quetiapine

  • Quinidine

  • Quinine

  • Ranolazine

  • Salmeterol

  • Sodium Phosphate

  • Sodium Phosphate, Dibasic

  • Sodium Phosphate, Monobasic

  • Solifenacin

  • Sorafenib

  • Sotalol

  • St John's Wort

  • Sunitinib

  • Telithromycin

  • Terfenadine

  • Tetrabenazine

  • Toremifene

  • Trimipramine

  • Vandetanib

  • Vardenafil

  • Vemurafenib

  • Venlafaxine

  • Voriconazole

  • Ziprasidone

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Atazanavir

  • Carbamazepine

  • Chlorpromazine

  • Clarithromycin

  • Digoxin

  • Foxglove

  • Indinavir

  • Itraconazole

  • Ketoconazole

  • Nefazodone

  • Phenytoin

  • Ritonavir

  • Thioridazine

  • Tipranavir

  • Trifluoperazine

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Bipolar disorder (mood disorder with alternating episodes of mania and depression), or risk of or

  • Bleeding problems or

  • Heart attack, recent or history of or

  • Heart disease or

  • Heart rhythm problems (e.g., QT prolongation) or

  • Hyponatremia (low sodium in the blood) or

  • Hypotension (low blood pressure) or

  • Priapism (painful or prolonged erection of the penis)—Use with caution. May make these conditions worse.

  • Kidney disease or

  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of trazodone

This section provides information on the proper use of a number of products that contain trazodone. It may not be specific to Desyrel. Please read with care.


Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.


This medicine should come with a medication guide. Read and follow these instructions carefully. Talk with your doctor if you have any questions.


To lessen stomach upset and to reduce dizziness and lightheadedness, take the regular tablets with or shortly after a meal or light snack, unless your doctor tells you otherwise.


Take the extended-release tablets at the same time each day, preferably at bedtime, without food.


The tablets can be swallowed whole or given as a half tablet by breaking the tablet along the score line. Do not break the tablets unless your doctor tells you to. Do not crush or chew the tablets.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For depression:
    • For oral dosage form (extended-release tablets):
      • Adults—At first, 150 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 375 mg per day.

      • Children—Use and dose must be determined by your doctor.


    • For oral dosage form (tablets):
      • Adults—At first, 150 milligrams (mg) per day, given in divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day.

      • Children—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using Desyrel


It is very important that your doctor check your progress at regular visits, to allow for changes in your dose and to help manage any side effects.


Do not stop taking this medicine without first checking with your doctor. To prevent a possible return of your medical problem, your doctor may want you to gradually reduce the amount of medicine you are using before you stop completely.


This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds; sedatives, tranquilizers or sleeping medicine; prescription pain medicine or narcotics; medicine for seizures or barbiturates; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using this medicine.


Before having any kind of surgery, dental treatment, or emergency treatment, tell the medical doctor or dentist in charge that you are using this medicine. Taking trazodone together with anesthetic medicines (numbing medicines) that are used during surgery, dental treatments, or emergency treatments may cause an increase in CNS depressant effects.


For some teenagers and young adults, this medicine can increase thoughts of suicide. Tell your doctor right away if you start to feel more depressed or have thoughts about hurting yourself or others. Report any unusual thoughts or behaviors that trouble you, especially if they are new or get worse quickly. Make sure the doctor knows if you have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. Also tell the doctor if you have sudden or strong feelings, such as feeling nervous, angry, restless, violent, or scared. Let the doctor know if you or anyone in your family have bipolar disorder (manic-depressive disorder) or have tried to commit suicide.


Make sure your doctor knows about all the other medicines you are using. This medicine may cause two serious conditions called serotonin syndrome and neuroleptic malignant syndrome (NMS)-like reactions when taken with certain medicines that are also used for depression, mental conditions, or migraines. Check with your doctor first before taking any other medicines. Stop taking this medicine and tell your doctor right away if you have more than one of the following symptoms: agitation; confusion; diarrhea; difficulty with breathing; a fast heartbeat; a high fever; high or low blood pressure; loss of bladder control; muscle twitching; overactive reflexes; poor coordination; restlessness; seizures; severe muscle stiffness; shivering; sweating; talking or acting with excitement; trembling or shaking that you are unable to control; unusually pale skin; or tiredness.


This medicine can cause changes in the heart rhythm, such as a condition called QT prolongation. It may change the way your heart beats, and cause fainting or serious side effects in some patients. Contact your doctor right away if you have any symptoms of heart rhythm problems, such as fast, pounding, or irregular heartbeats.


This medicine may cause some people to become drowsy or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert.


Dizziness, lightheadedness, or fainting may occur, especially when you get up suddenly from a lying or sitting position. Getting up slowly may help. If this problem continues or gets worse, check with your doctor.


Trazodone may cause dryness of the mouth. For temporary relief, use sugarless gum or candy, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.


Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.


Desyrel Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


More common
  • Blurred vision

  • confusion

  • dizziness

  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

  • lightheadedness

  • sweating

  • unusual tiredness or weakness

Less common
  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

  • confusion about identity, place, and time

  • decreased concentration

  • fainting

  • general feeling of discomfort or illness

  • headache

  • lack of coordination

  • muscle tremors

  • nervousness

  • pounding in the ears

  • shortness of breath

  • slow or fast heartbeat

  • swelling

Rare
  • Skin rash

  • unusual excitement

Get emergency help immediately if any of the following symptoms of overdose occur:


Symptoms of overdose
  • Drowsiness

  • loss of muscle coordination

  • nausea and vomiting

  • painful, inappropriate erection of the penis, continuing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Dryness of the mouth (usually mild)

  • muscle or bone pain

  • sleeplessness

  • trouble with remembering

  • trouble with sleeping

  • unable to sleep

  • unpleasant taste

Less common
  • Constipation

  • continuing ringing or buzzing or other unexplained noise in the ears

  • diarrhea

  • hearing loss

  • muscle aches or pains

  • weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Desyrel side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Desyrel resources


  • Desyrel Side Effects (in more detail)
  • Desyrel Use in Pregnancy & Breastfeeding
  • Drug Images
  • Desyrel Drug Interactions
  • Desyrel Support Group
  • 22 Reviews for Desyrel - Add your own review/rating


  • Desyrel Prescribing Information (FDA)

  • Desyrel MedFacts Consumer Leaflet (Wolters Kluwer)

  • Oleptro Prescribing Information (FDA)

  • Oleptro Extended-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

  • Oleptro Consumer Overview

  • Trazodone Prescribing Information (FDA)

  • Trazodone Hydrochloride Monograph (AHFS DI)



Compare Desyrel with other medications


  • Anxiety
  • Depression
  • Fibromyalgia
  • Insomnia
  • Reflex Sympathetic Dystrophy Syndrome
  • Sedation

desonide topical


Generic Name: desonide topical (DES oh nide)

Brand names: Delonide, Desonate, DesOwen, DesOwen 2 oz, DesOwen Lotion 4 oz Kit, LoKara, Tridesilon, Verdeso, DesOwen Lotion 2 oz Kit, DesOwen Cream Kit, DesOwen Ointment Kit, Desonil+Plus Cream, Desonil+Plus Ointment


What is desonide topical?

Desonide is a topical (for the skin) steroid. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling.


Desonide topical is used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis.


Desonide topical may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about desonide topical?


Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body.


Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with desonide topical can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions. Do not use this medication on a child without a doctor's advice. Children are more likely to absorb large amounts of a topical steroid through the skin. Steroid absorption in children may cause unwanted side effects, or a delay in growth with long-term use. Talk with your doctor if you think your child is not growing at a normal rate while using this medication over a long treatment period. Contact your doctor if your condition does not improve after 2 weeks of using this medicine, or if you develop signs of a bacterial, fungal, or viral skin infection.

What should I discuss with my healthcare provider before using desonide topical?


Do not use this medication if you are allergic to desonide.

Before using desonide topical, tell your doctor if you are allergic to any drugs, or if you have any type of skin infection.


Also tell your doctor if you have diabetes. Topical steroid medicines absorbed through the skin may increase the glucose (sugar) levels in your blood or urine.


FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether desonide topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medication on a child without a doctor's advice. Children are more likely to absorb large amounts of a topical steroid through the skin. Steroid absorption in children may cause unwanted side effects, or a delay in growth with long-term use. Talk with your doctor if you think your child is not growing at a normal rate while using this medication over a long treatment period.

How should I use desonide topical?


Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body.


Wash your hands before and after using desonide topical, unless you are using the medication to treat the skin on your hands.

Apply a small amount to the affected area and rub it gently into the skin. Do not use this medication over a large area of skin.


Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with desonide topical can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions. Contact your doctor if your condition does not improve after 2 weeks of using this medicine, or if you develop signs of a bacterial, fungal, or viral skin infection. It is important to use desonide topical regularly to get the most benefit.

To be sure this medication is not causing harmful effects with long-term use, you may need blood tests. Do not miss any scheduled appointments.


Store desonide topical at room temperature away from moisture and heat. Keep from freezing.

What happens if I miss a dose?


Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of desonide is not expected to produce life-threatening symptoms. However, long-term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


What should I avoid while using desonide topical?


Desonide topical should not be used to treat any skin condition your doctor has not prescribed it for.


Avoid getting this medication in your eyes. If contact does occur, rinse with water. Do not use desonide topical on broken or infected skin. Also avoid using this medication in open wounds.

Desonide topical side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing desonide topical through your skin, such as:

  • blurred vision, or seeing halos around lights;




  • mood changes;




  • sleep problems (insomnia);




  • weight gain, puffiness in your face; or




  • muscle weakness, feeling tired.



Less serious side effects may include:



  • mild skin itching, redness, burning, or peeling;




  • dryness or scaly skin;




  • thinning or softening of your skin;




  • skin rash or irritation around your mouth;




  • swollen hair follicles;




  • changes in color of treated skin;




  • blisters, pimples, or crusting of treated skin; or




  • stretch marks.



This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.


Desonide topical Dosing Information


Usual Adult Dose for Dermatitis:

Cream, lotion and ointment:
Apply a thin film to the affected areas two or three times a day.

Foam and gel for atopic dermatitis:
Apply a thin film to the affected areas two times a day.

Usual Adult Dose for Eczema:

Cream, lotion and ointment:
Apply a thin film to the affected areas two or three times a day.

Foam and gel for atopic dermatitis:
Apply a thin film to the affected areas two times a day.

Usual Adult Dose for Psoriasis:

Cream, lotion and ointment:
Apply a thin film to the affected areas two or three times a day.

Foam and gel for atopic dermatitis:
Apply a thin film to the affected areas two times a day.

Usual Pediatric Dose for Dermatitis:

3 months or older:
Foam and gel for atopic dermatitis:
Apply a thin film to the affected areas two times a day.

1 year or older:
Cream, lotion and ointment:
Apply a thin film to the affected areas two or three times a day.

Usual Pediatric Dose for Eczema:

3 months or older:
Foam and gel for atopic dermatitis:
Apply a thin film to the affected areas two times a day.

1 year or older:
Cream, lotion and ointment:
Apply a thin film to the affected areas two or three times a day.

Usual Pediatric Dose for Psoriasis:

3 months or older:
Foam and gel for atopic dermatitis:
Apply a thin film to the affected areas two times a day.

1 year or older:
Cream, lotion and ointment:
Apply a thin film to the affected areas two or three times a day.


What other drugs will affect desonide topical?


It is not likely that other drugs you take orally or inject will have an effect on topically applied desonide topical. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.



More desonide topical resources


  • Desonide topical Side Effects (in more detail)
  • Desonide topical Use in Pregnancy & Breastfeeding
  • Desonide topical Drug Interactions
  • Desonide topical Support Group
  • 17 Reviews for Desonide - Add your own review/rating


  • DesOwen Cream MedFacts Consumer Leaflet (Wolters Kluwer)

  • DesOwen Cream Kit Cream MedFacts Consumer Leaflet (Wolters Kluwer)

  • Desonate Consumer Overview

  • Desonate Advanced Consumer (Micromedex) - Includes Dosage Information

  • Desonate Gel MedFacts Consumer Leaflet (Wolters Kluwer)

  • Desonate Prescribing Information (FDA)

  • Desowen Prescribing Information (FDA)

  • LoKara Prescribing Information (FDA)

  • LoKara Lotion MedFacts Consumer Leaflet (Wolters Kluwer)

  • Verdeso Prescribing Information (FDA)

  • Verdeso Consumer Overview

  • Verdeso Foam MedFacts Consumer Leaflet (Wolters Kluwer)



Compare desonide topical with other medications


  • Atopic Dermatitis
  • Dermatitis
  • Eczema
  • Psoriasis


Where can I get more information?


  • Your pharmacist can provide more information about desonide topical.

See also: desonide side effects (in more detail)


DeWilt's Pain Reliever


Pronunciation: mag-NEE-zee-uhm sal-i-SIL-ate
Generic Name: Magnesium Salicylate
Brand Name: Examples include Doan's Pills and DeWitt's Pain Reliever


DeWilt's Pain Reliever is used for:

Treating minor backache pain. It may also be used for other conditions as determined by your doctor.


DeWilt's Pain Reliever is a salicylate. It works by blocking certain chemicals in the body that cause pain, inflammation, and fever.


Do NOT use DeWilt's Pain Reliever if:


  • you are allergic to any ingredient in DeWilt's Pain Reliever or you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties, dizziness) to aspirin or an NSAID (eg, ibuprofen, naproxen, celecoxib)

  • you are a child or teenager with influenza (flu) or chickenpox

  • you have bleeding problems such as hemophilia, von Willebrand disease, or low blood platelets

  • you are taking anticoagulants (eg, heparin, warfarin) or methotrexate

Contact your doctor or health care provider right away if any of these apply to you.



Before using DeWilt's Pain Reliever:


Some medical conditions may interact with DeWilt's Pain Reliever. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have alcoholism or if you consume 3 or more alcohol-containing drinks every day

  • if you have asthma, bleeding or clotting problems, diabetes, gout, arthritis, growths in the nose (nasal polyps), kidney or liver problems, stomach or peptic ulcers (bleeding ulcers), heartburn, upset stomach, stomach pain, influenza (flu) or chickenpox, or vitamin K deficiency

  • if you have a history of stroke or a weakened blood vessel (cerebral aneurysm) or bleeding in the brain

  • if you have Kawasaki syndrome (a rare inflammation causing heart problems in children)

Some MEDICINES MAY INTERACT with DeWilt's Pain Reliever. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Carbonic anhydrase inhibitors (eg, acetazolamide) because they may decrease DeWilt's Pain Reliever's effectiveness

  • Anticoagulants (eg, heparin, warfarin) or NSAIDs (eg, ibuprofen, celecoxib) because the risk of their side effects, including risk of bleeding, may be increased by DeWilt's Pain Reliever

  • Insulin and oral antidiabetics (eg, glyburide, nateglinide) because the risk of their side effects, including abnormally low blood sugar level (eg, hunger, shakiness or weakness, dizziness, headache, sweating), may be increased by DeWilt's Pain Reliever

  • Methotrexate or valproic acid because the risk of their side effects may be increased by DeWilt's Pain Reliever

  • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), probenecid, or sulfinpyrazone because their effectiveness may be decreased by DeWilt's Pain Reliever

This may not be a complete list of all interactions that may occur. Ask your health care provider if DeWilt's Pain Reliever may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use DeWilt's Pain Reliever:


Use DeWilt's Pain Reliever as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take DeWilt's Pain Reliever by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

  • Take DeWilt's Pain Reliever with a full glass of water (8 oz/240 mL). Do not lie down for 30 minutes after taking DeWilt's Pain Reliever.

  • Use DeWilt's Pain Reliever exactly as directed on the package, unless instructed differently by your doctor. If you are taking DeWilt's Pain Reliever without a prescription, follow any warnings and precautions on the label.

  • If you miss a dose of DeWilt's Pain Reliever and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use DeWilt's Pain Reliever.



Important safety information:


  • Talk to your doctor before you take DeWilt's Pain Reliever if you drink more than 3 drinks with alcohol per day.

  • DeWilt's Pain Reliever may cause stomach bleeding. Your risk may be greater if you drink alcohol while you are using DeWilt's Pain Reliever.

  • DeWilt's Pain Reliever may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.

  • DeWilt's Pain Reliever has a salicylate in it. Before you start any new medicine, check the label to see if it has a salicylate in it too. If it does or if you are not sure, check with your doctor or pharmacist.

  • DeWilt's Pain Reliever has a salicylate in it, which has been linked to a serious illness called Reye syndrome. Do not give DeWilt's Pain Reliever to a child or teenager who has the flu, chickenpox, or a viral infection. Contact your doctor with any questions or concerns.

  • If DeWilt's Pain Reliever has a strong vinegar-like smell upon opening, do not use. It means the medicine is breaking down. Throw the bottle away safely and out of the reach of children; contact your pharmacist and replace.

  • Tell your doctor or dentist that you take DeWilt's Pain Reliever before you receive any medical or dental care, emergency care, or surgery.

  • Do not take DeWilt's Pain Reliever for at least 7 days after any surgery unless directed by your health care provider.

  • Do not take DeWilt's Pain Reliever for more than 10 days for pain or for more than 3 days for fever unless directed to do so by your health care provider.

  • Different brands of DeWilt's Pain Reliever may have different dosing instructions for CHILDREN. Follow the dosing instructions on the package labeling. If your doctor has given you instructions, follow those. If you are unsure of the dose to give a child, check with your doctor or pharmacist.

  • PREGNANCY and BREAST-FEEDING: Do not use DeWilt's Pain Reliever during the last 3 months of pregnancy; it may cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using DeWilt's Pain Reliever while you are pregnant. DeWilt's Pain Reliever is found in breast milk. If you are or will be breast-feeding while you use DeWilt's Pain Reliever, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of DeWilt's Pain Reliever:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Heartburn; nausea; upset stomach.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or bloody stools; confusion; diarrhea; dizziness; drowsiness; hearing loss; ringing in the ears; severe stomach pain; vomiting.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: DeWilt's Pain Reliever side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include agitation; fever; hearing loss; lethargy; lightheadedness, especially upon standing; nausea; rapid breathing; rapid or irregular heartbeat; ringing in the ears; seizures; shortness of breath; stomach pain; vomiting.


Proper storage of DeWilt's Pain Reliever:

Store DeWilt's Pain Reliever at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep DeWilt's Pain Reliever out of the reach of children and away from pets.


General information:


  • If you have any questions about DeWilt's Pain Reliever, please talk with your doctor, pharmacist, or other health care provider.

  • DeWilt's Pain Reliever is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about DeWilt's Pain Reliever. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More DeWilt's Pain Reliever resources


  • DeWilt's Pain Reliever Side Effects (in more detail)
  • DeWilt's Pain Reliever Use in Pregnancy & Breastfeeding
  • DeWilt's Pain Reliever Drug Interactions
  • 0 Reviews for DeWilt's Pain Reliever - Add your own review/rating


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  • Inflammatory Conditions
  • Pain

DesOwen 2 oz


Generic Name: desonide topical (DES oh nide)

Brand Names: Delonide, Desonate, DesOwen, DesOwen 2 oz, DesOwen Lotion 4 oz Kit, LoKara, Tridesilon, Verdeso


What is DesOwen 2 oz (desonide topical)?

Desonide is a topical (for the skin) steroid. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling.


Desonide topical is used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis.


Desonide topical may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about DesOwen 2 oz (desonide topical)?


Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body.


Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with desonide topical can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions. Do not use this medication on a child without a doctor's advice. Children are more likely to absorb large amounts of a topical steroid through the skin. Steroid absorption in children may cause unwanted side effects, or a delay in growth with long-term use. Talk with your doctor if you think your child is not growing at a normal rate while using this medication over a long treatment period. Contact your doctor if your condition does not improve after 2 weeks of using this medicine, or if you develop signs of a bacterial, fungal, or viral skin infection.

What should I discuss with my healthcare provider before using DesOwen 2 oz (desonide topical)?


Do not use this medication if you are allergic to desonide.

Before using desonide topical, tell your doctor if you are allergic to any drugs, or if you have any type of skin infection.


Also tell your doctor if you have diabetes. Topical steroid medicines absorbed through the skin may increase the glucose (sugar) levels in your blood or urine.


FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether desonide topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medication on a child without a doctor's advice. Children are more likely to absorb large amounts of a topical steroid through the skin. Steroid absorption in children may cause unwanted side effects, or a delay in growth with long-term use. Talk with your doctor if you think your child is not growing at a normal rate while using this medication over a long treatment period.

How should I use DesOwen 2 oz (desonide topical)?


Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body.


Wash your hands before and after using desonide topical, unless you are using the medication to treat the skin on your hands.

Apply a small amount to the affected area and rub it gently into the skin. Do not use this medication over a large area of skin.


Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with desonide topical can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions. Contact your doctor if your condition does not improve after 2 weeks of using this medicine, or if you develop signs of a bacterial, fungal, or viral skin infection. It is important to use desonide topical regularly to get the most benefit.

To be sure this medication is not causing harmful effects with long-term use, you may need blood tests. Do not miss any scheduled appointments.


Store desonide topical at room temperature away from moisture and heat. Keep from freezing.

What happens if I miss a dose?


Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of desonide is not expected to produce life-threatening symptoms. However, long-term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


What should I avoid while using DesOwen 2 oz (desonide topical)?


Desonide topical should not be used to treat any skin condition your doctor has not prescribed it for.


Avoid getting this medication in your eyes. If contact does occur, rinse with water. Do not use desonide topical on broken or infected skin. Also avoid using this medication in open wounds.

DesOwen 2 oz (desonide topical) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing desonide topical through your skin, such as:

  • blurred vision, or seeing halos around lights;




  • mood changes;




  • sleep problems (insomnia);




  • weight gain, puffiness in your face; or




  • muscle weakness, feeling tired.



Less serious side effects may include:



  • mild skin itching, redness, burning, or peeling;




  • dryness or scaly skin;




  • thinning or softening of your skin;




  • skin rash or irritation around your mouth;




  • swollen hair follicles;




  • changes in color of treated skin;




  • blisters, pimples, or crusting of treated skin; or




  • stretch marks.



This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect DesOwen 2 oz (desonide topical)?


It is not likely that other drugs you take orally or inject will have an effect on topically applied desonide topical. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.



More DesOwen 2 oz resources


  • DesOwen 2 oz Side Effects (in more detail)
  • DesOwen 2 oz Use in Pregnancy & Breastfeeding
  • DesOwen 2 oz Drug Interactions
  • DesOwen 2 oz Support Group
  • 5 Reviews for DesOwen 2 oz - Add your own review/rating


  • DesOwen Cream MedFacts Consumer Leaflet (Wolters Kluwer)

  • DesOwen Cream Kit Cream MedFacts Consumer Leaflet (Wolters Kluwer)

  • Desonate Consumer Overview

  • Desonate Advanced Consumer (Micromedex) - Includes Dosage Information

  • Desonate Gel MedFacts Consumer Leaflet (Wolters Kluwer)

  • Desonate Prescribing Information (FDA)

  • Desowen Prescribing Information (FDA)

  • LoKara Prescribing Information (FDA)

  • LoKara Lotion MedFacts Consumer Leaflet (Wolters Kluwer)

  • Verdeso Prescribing Information (FDA)

  • Verdeso Consumer Overview

  • Verdeso Foam MedFacts Consumer Leaflet (Wolters Kluwer)



Compare DesOwen 2 oz with other medications


  • Atopic Dermatitis
  • Dermatitis
  • Eczema
  • Psoriasis


Where can I get more information?


  • Your pharmacist can provide more information about desonide topical.

See also: DesOwen 2 oz side effects (in more detail)